Somnolence - Wikipedia, the free encyclopedia
Somnolence
From Wikipedia, the free encyclopedia
Somnolence (or drowsiness ) is a state of near-sleep , a strong desire for sleep, or sleeping for unusually long periods (cf. hypersomnia ). It has two distinct meanings, referring both to the usual state preceding falling asleep, and the chronic condition referring to being in that state independent of a circadian rhythm . Somnolence goes back to the Latin somnus meaning sleep.
[edit ] Hazards
Sleepiness can be dangerous when performing tasks that require constant concentration, such as driving a vehicle . When a person is sufficiently fatigued , he or she may experience microsleeps .
[edit ] Illness
The human body can become sleepy in response to infection .[ 1] Such somnolence is one of several sickness behaviors or reactions to infection that some theorize evolved to promote recovery by conserving energy while the body fights the infection using fever and other means.[ 2] [ 3]
[edit ] Associated conditions
Alice in Wonderland syndrome
brain edema
cerebral hypoxia
Chronic Mental Fatigue Syndrome
clinical depression , especially seasonal affective disorder (SAD)
dehydration , due to overall decrease in blood pressure
delayed sleep phase syndrome
diabetes – ketoacidosis as example, but not balanced diabetes mellitus
encephalitis – (viral, bacterial or other agents)
epilepsy – after seizure
hydrocephalus
hyperparathyroidism
hypothermia
hypothyroidism
infectious mononucleosis (glandular fever)
intracranial hemorrhage such as due to ruptured aneurysm
increased intracranial pressure ; for example, due to brain tumors
Lyme disease (borreliosis)
medications
analgesics – mostly prescribed or illicit opiates such as OxyContin or heroin
anticonvulsants / antiepileptics – such as phenytoin (Dilantin), carbamazepine (Tegretol), lamotrigine (Lamictal), Lyrica (pregbalin), Gabapentin
antidepressants – for instance, sertraline , venlafaxine and fluoxetine
antihistamines – for instance, diphenhydramine (Benadryl) and doxylamine (Unisom-2)
antipsychotics – for example, thioridazine , quetiapine , and olanzapine (Zyprexa) and haloperidol and Geodon .
dopamine agonists used in the treatment of Parkinson's disease – e.g. pergolide and ropinirole and Mirapex , used to treat restless leg syndrome .
HIV medications – for example, Sustiva and medications containing efavirenz
Hormone replacement therapy (male-to-female) [ 4]
hypertension medications – such as Norvasc
tranquilizers / hypnotics – especially benzodiazepines, such as temazepam (Restoril) or nitrazepam (Mogadon), and barbiturates , such as amobarbital (Amytal) or secobarbital (Seconal)
other agents impacting the central nervous system , in sufficient or toxic doses
narcolepsy
sickness behavior
sleep apnea
sleep deprivation / insomnia
starvation
stroke
traumatic brain injury
trypanosomiasis
[edit ] See also
[edit ] References
^ Mullington, J.; Korth, C.; Hermann, D.M.; Orth, A.; Galanos, C.; Holsboer, F.; Pollmacher, T. (2000) Dose-dependent effects of endotoxin on human sleep . Am J Physiol Regul Integr Comp Physiol. 278: R947–955 PubMed
^ Hart, B.L. (1988) Biological basis of the behavior of sick animals. Neurosci Biobehav Rev. 12: 123–137. PubMed
^ Kelley, K.W.; Bluthe, R.M.; Dantzer, R.; Zhou, J.H.; Shen, W.H.; Johnson, R.W.; Broussard, S.R. (2003) Cytokine-induced sickness behavior. Brain Behav Immun. 17 Suppl 1: S112–118 PubMed
^ The World Professional Association for Transgender Health's Standards of Care, 6th version